Regrowing Limbs: Can People Regenerate Body Parts?: Scientific American

"Progress on the road to regenerating major body parts, salamander-style, could transform the treatment of amputations and major wounds

By Ken Muneoka, Manjong Han and David M. Gardiner Aaron Goodman

Key Concepts
* The gold standard for limb regeneration is the salamander, which can grow perfect replacements for lost body parts throughout its lifetime. Understanding how can provide a road map for human limb regeneration.

* The early responses of tissues at an amputation site are not that different in salamanders and in humans, but eventually human tissues form a scar, whereas the salamander's reactivate an embryonic development program to build a new limb.

* Learning to control the human wound environment to trigger salamander like healing could make it possible to regenerate large body parts."